Rajendra Sharma - Leaky Gut
small intestine acts like a selective sieve, allowing through
into the blood stream only the breakdown products of digestion.
Larger proteins, carbohydrates and fats are kept out permitting
only the amino acids and short chain peptides from proteins,
single or double sugar molecules (mono-saccarides or di-saccarides)
from carbohydrates and small chain fatty acids from fats to
enter the blood stream.
larger may be recognised by the body as an invading particle and
an immune response is initiated. Foods that are not fully digested
are absorbed into the blood stream and the body sets up an allergic
or immune response that will, from that time on if not treated,
recognise basic foods as if they were bacteria or viruses and, potentially,
set up an attack.
are many causes of a leaky gut as anything that inflames the bowel
may cause the syndrome. Parasitic, fungal or yeast, bacterial or
viral infection are often a cause. Anything that can or does diminish
the bowel's natural flora are more common causes. These include
anti-biotics, either prescribed by the doctor or found inadvertently
in processed foods, chemical toxins such as pesticides, preservatives
and additives may also be culprits.
produces an acidic response from the stomach that can alter the
bowel pH which may have an effect and excess adrenaline cuts down
the blood flow to the bowel, reducing oxygen and nutrients, allowing
deterioration of the bowel wall.
recent study in the British Journal of Nutrition (2000;83:000-000)
has drawn a connection between rheumatoid arthritis and a leaky
gut and even the ultra orthodox New England Journal of Medicine
(Albert LJ and Inman RD, 2000;341(27):2068-2074) has published a
review article supporting the possibility of multiple sclerosis
being associated with the body recognising protein sequences in
foreign substances which resemble the body's own thereby causing
an attack on the nervous system
conditions with evidence of being caused or worsened by the presence
of increased intestinal permeability are: Inflammatory Bowel Disease,
Ankylosing Spondilitis, Crohns' Disease, allergic disorders such
as Asthma, Hayfever and Eczema, Schizophrenia and Migraines.
for a Leaky Gut The Polyethylene Glycol (PEG) test
orthodox medical world does not recognise this as a medical condition
- yet. There are laboratories in the United States and one here
in the United Kingdom that test for this condition using a very
solution of inert (indigestible and unusable) molecules is drunk
and, having emptied the bladder previously, urine is collected for
the next six hours. At the end of this time the sample is shaken
and a small portion sent to the laboratory. A certain percentage
of the small molecules should have passed through the gut wall,
into the blood stream and been filtered out by the kidneys into
the urine. The larger molecules that were drunk should not have
got through and simply pass out with the faeces. The presence of
any large molecules, therefore, in the urine indicates the presence
of increased intestinal permeability - the leaky gut syndrome.
this time instructions and collection kits can be sent to an individual.
Once the sample is collected it is returned directly to The Diagnostic
Clinic and results returned, usually, within 7 days.
Leaky Gut Syndrome is frequently associated with yeast or fungal
infections including Candida. A test called The Gut Fermentation
study can give practitioners information regarding the presence
of yeast. This simple test involves the patient taking a sugary
capsule or drink and an hour later having a blood sample taken to
look for alcohols in the blood. This appears because of the fermentation
of sugar by yeasts. This test also gives information about a lack
of dietary fibre, possible hypoglycaemia and the presence of good
and bad bowel flora.
Allergy Cellular Test is the test of choice regarding food allergy.
This looks for a particular inflammatory compound that comes out
of White Blood Cells in the presence of an allergic food. Food allergy
is a main issue either causative or as an effect of a leaky gut.
Food intolerance testing
for food intolerance can be done using a Bioresonance computer.
The Diagnostic Clinic's choice is the QX Quantum CI in the hands
of a specialised nutritionist.
- Stomach acid production assay
digestion can leave large undigested molecules in the small intestine
that can damage the inner or epithelial lining of the gut. These
larger molecules may also be more likely to trigger an immune response.
A new test called BioHit is a blood test that allows us to tell
if the stomach lining is producing the correct quantity of acid
to ensure breakdown of food.
a leaky gut is established and symptoms of ill health can be associated
with this then treatment is a prerequisite for a return to good
health. Current treatment protocol includes high dose acidophillus
(to replenish bowel bacteria and challenge yeast i.e. Candida, infection),
herbal antibacterial extracts including berberine from berberis,
a special clay powder that releases oxygen into the bowel (most
bad bacteria are anaerobic - they don't live in oxygen), herbal
extracts known to increase the integrity of mucosal (gut lining)
cells and the protein glutamine - a protein essential for bowel
membrane integrity. A diet avoiding fermentable foods - an anti-candida
diet is recommended strongly along side the treatments regardless
of the evidence for yeast infection as these diets tend to be hypo-allergenic
in any case.
Sharma's Leaky Gut Protocol
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- Gastropax (4 days) Bentonite-like
clay combination - one teaspoonful in warm water tds before meals
(1 Bottle) Herbal combination - 20 drops in a little warm water
½ hour pre meals £18.25
High potency bifido-acidophillus - 1 sachet daily £29.96
- Berberis Tincture
Anti-dysbiotic herbal extract - 2 teaspoonsful twice daily (250mls)
in pineapple juice £15.00
- L - Glutamine
Precursor to the bowel epithelial lining - 1 capsule three times
daily with meals £10.50. £89.96 + P&P
Dr Rajendra Sharma is a fully qualified doctor specialising
in Integrated Medicine and the Medical Director of The Diagnostic
Clinic. His protocol can be prescribed by practitioners who
can obtain the preferred products mentioned above via The Dispensary
01202 744 717. You can vist The Diagnostic Clinic website at
Medical Disclaimer The advice given is in no way meant to
take the place of professional advice. Should you wish to consider
any level of treatment we strongly advise you to run this past
your GP or health professional.